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|Composition||Dolutegravir emtricitabine and tenvir|
Spegra Tablet 30's contains 'Dolutegravir, Emtricitabine and Tenofovir alafenamide'. Spegra Tablet 30's works by interfering with the working of HIV-1 reverse transcriptase enzymes which are necessary for the replication of the virus. Together, Spegra Tablet 30's helps in treating HIV infection.
Take Spegra Tablet 30's as prescribed. In some cases, Spegra Tablet 30's may cause certain side effects such as trouble sleeping, headache, nausea, and tiredness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.
Consult your doctor if you are pregnant, or planning to get pregnant. Avoid breastfeeding while taking Spegra Tablet 30's. Spegra Tablet 30's does not help reduce the risk of getting HIV-1 infection by sexual contact; therefore, it is important to practise safe sex to avoid transmitting HIV to your partner. Avoid alcohol consumption while on treatment with Spegra Tablet 30's.Uses of Spegra Tablet 30's
HIV-1 infectionMedicinal Benefits
Spegra Tablet 30's is an anti-retroviral drug used in the treatment of HIV-1 infection. Spegra Tablet 30's works by interfering with the replication of HIV and preventing its further progression. It contains Dolutegravir, Emtricitabine and Tenofovir alafenamide. Dolutegravir works by blocking HIV integrase, which is responsible for integrating viral DNA into the host cell. Thus, it inhibits the integration of the viral component into the human body cells. Emtricitabine works by inhibiting reverse transcriptase, which is responsible for transcribing RNA to DNA. By blocking this action, emtricitabine prevents the proliferation of the virus. Tenofovir alafenamide blocks the enzyme polymerase, thereby preventing aggregation of viral components and terminating the DNA chain, thus effectively nipping viral replication in the bud.Directions for UseSwallow Spegra Tablet 30's as a whole with water. Do not crush, chew or break it.StorageStore in a cool and dry place away from sunlightSide Effects of Spegra Tablet 30's
Inform the doctor if you are allergic to any of the components of Spegra Tablet 30's. Consult your doctor if you are pregnant, or planning to get pregnant before taking Spegra Tablet 30's. Avoid breastfeeding while on treatment with Spegra Tablet 30's. Avoid alcohol consumption. It is important to practise safe sex to avoid transmitting HIV to your partner. Inform your doctor if you have liver problems, hepatitis infections, heart or kidney problems. Keep your doctor informed about your health condition and medications to rule out any interactions.Drug Interactions
Drug-Drug Interactions: Spegra Tablet 30's may interact with antiviral/anti-HIV drug (adefovir dipivoxil, atazanavir, bictegravir, lamivudine), anti-Tb drug (rifampicin), antidepressant (St John’s wort), ulcer medicine (sucralfate), antibiotics (azithromycin, clarithromycin, rifabutin), immunosuppressants (cyclosporine), anti-epileptics (phenobarbital or phenytoin), antacids, iron supplements and vitamins.
Drug-Food Interactions: No interactions found.
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