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Olaparib is used alone or in combination with bevacizumab (Avastin) to help maintain the response of certain types of ovarian (female reproductive organs where eggs are formed), fallopian tube (tube that transports eggs released by the ovaries to the uterus), and peritoneal (layer of tissue that lines the abdomen) cancer in people who have completely responded or partially responded to their first or later chemotherapy treatments. Olaparib is also used to treat certain types of breast cancer that has spread to other parts of the body and has not improved or has worsened after treatment with other therapies. It is also used to treat certain types of early breast cancer in people who have already been treated with other chemotherapy treatments. Olaparib is also used to treat a certain type of prostate cancer that has spread to other parts of the body, no longer responds to medical or surgical treatments to lower testosterone levels, and has progressed after treatment with enzalutamide (Xtandi) or abiraterone (Yonsa, Zytiga). Olaparib is also used to treat ovarian cancer that has not improved or has worsened after treatment with at least three other therapies. Olaparib is also used to help maintain the response of a certain type of pancreatic cancer that has not spread or progressed after the first chemotherapy treatment. Olaparib is a polyadenosine 5'-diphosphoribose polymerase (PARP) enzyme inhibitor. It works by killing cancer cells.

Additional Information:

• Item Code: 35654
• Production Capacity: 122545
• Delivery Time: 5days
• Packaging Details: Lynparza...reinforces our growing capabilities in innovation and clinical research for providing holistic solutions for cancer treatment in India," AstraZeneca India Managing Director and Country President Gagandeep Singh noted. Breast cancer is one of the most diagnosed cancer worldwide with an estimated 23 lakh patients diagnosed per year. Non-Communicable Diseases (NCDs) like cancer in India today account for 62 per cent of all deaths and 48 per cent of preventable premature deaths.

Apalutamide is used to treat prostate cancer that has spread to other parts of the body (metastatic) and is also being treated with another medicine or with surgery.

Apalutamide is also used to treat prostate cancer that has not spread to other parts of the body, after surgery or other cancer treatments did not work or have stopped working.

Apalutamide is used together with a gonadotropin-releasing hormone (GnRH) or with surgical castration (removal of the testicles).

Warnings

Although apalutamide is not for use by women, this medicine can cause birth defects if a woman is exposed to it during pregnancy.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

Apalutamide is not for use by women or children.

Apalutamide can harm an unborn baby or cause miscarriage. Apalutamide can also harm an unborn baby if the father is taking this medicine at the time of conception or during pregnancy.

Use effective birth control if your sex partner is able to become pregnant. Use condoms if your sex partner is pregnant. Keep using effective birth control and condoms for at least 3 months after your last dose of this medicine.

Apalutamide may affect fertility (your ability to have children). However, it is important to use birth control to prevent pregnancy because apalutamide may harm the baby if a pregnancy does occur.

Also do not donate sperm while you are taking this medicine, and during the 3 months after your last dose.

To make sure this medicine is safe for you, tell your doctor if you have:

• a head injury or brain tumor;

• a seizure;

• a stroke;

• heart disease, high blood pressure;

• diabetes; or

• abnormal levels of cholesterol or fats in your blood.

Hormonal cancer treatment can weaken your muscles and bones. You may be more likely to have a broken bone while using apalutamide. Talk with your doctor about ways to keep your bones healthy.

Apalutamide pregnancy and breastfeeding warnings (more detail)

Additional Information:

• Item Code: 358525146
• Production Capacity: 2155
• Delivery Time: 3 DAYS
• Packaging Details: Apalutamide is used to treat prostate cancer that has spread to other parts of the body (metastatic) and is also being treated with another medicine or with surgery. Apalutamide is also used to treat prostate cancer that has not spread to other parts of the body, after surgery or other cancer treatments did not work or have stopped working. Apalutamide is used together with a gonadotropin-releasing hormone (GnRH) or with surgical castration (removal of the testicles). Warnings Although apalutamide is not for use by women, this medicine can cause birth defects if a woman is exposed to it during pregnancy. Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Before taking this medicine Apalutamide is not for use by women or children. Apalutamide can harm an unborn baby or cause miscarriage. Apalutamide can also harm an unborn baby if the father is taking this medicine at the time of conception or during pregnancy. Use effective birth control if your sex partner is able to become pregnant. Use condoms if your sex partner is pregnant. Keep using effective birth control and condoms for at least 3 months after your last dose of this medicine. Apalutamide may affect fertility (your ability to have children). However, it is important to use birth control to prevent pregnancy because apalutamide may harm the baby if a pregnancy does occur. Also do not donate sperm while you are taking this medicine, and during the 3 months after your last dose. To make sure this medicine is safe for you, tell your doctor if you have: a head injury or brain tumor; a seizure; a stroke; heart disease, high blood pressure; diabetes; or abnormal levels of cholesterol or fats in your blood. Hormonal cancer treatment can weaken your muscles and bones. You may be more likely to have a broken bone while using apalutamide. Talk with your doctor about ways to keep your

Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) 5. It was initially approved in the USA in 1990's for the treatment of NSCLC 13.

It is a third-generation vinca alkaloid. The introduction of third-generation drugs (vinorelbine, gemcitabine, taxanes) in platinum combination improved survival of patients with advanced NSCLC, with very similar results from the various drugs. Treatm

Additional Information:

• Item Code: 31254682
• Production Capacity: 2000
• Delivery Time: 5 days
• Packaging Details: Vinorelbine tartrate is indicated for adults in the treatment of advanced non-small cell lung cancer (NSCLC), as a single therapy or in combination with other chemotherapeutic drugs 5. Used in relapsed or refractory Hodgkin lymphoma, in combination with other chemotherapy agents 14. For the treatment of desmoid tumor or aggressive fibromatosis, in combination with methotrexate 14. For the treatment of recurrent or metastatic squamous cell head and neck cancer 14. For the treatment of recurrent ovarian cancer 14. For the treatment of metastatic breast cancer, in patients previously treated with anthracyline and/or taxane therapy 14. For the treatment of HER2-positive, trastuzumab-resistant, advanced breast cancer in patients previously treated with a taxane, in combination with trastuzumab and everolimus 14. Build, train, & validate predictive machine-learning models with structured datasets. Associated Conditions Locally Advanced Non-Small Cell Lung Cancer Metastatic Breast Cancer Metastatic Cervical Cancer Metastatic Non-Small Cell Lung Cancer Recurrent Cervical Cancer Soft Tissue Sarcoma Contraindications & Blackbox Warnings Avoid life-threatening adverse drug events & improve clinical decision support. Pharmacodynamics Vinorelbine is a semi-synthetic vinca-alkaloid with a wide spectrum of anti-tumor activity. The vinca-alkaloids are considered spindle poisons. They work by interfering with the polymerization of tubulin, a protein responsible for building the microtubule system which appears during cell division in proliferating cancer cells 11. Mechanism of action Vinca alkaloids are structurally similar compounds composed of two multi-ringed units, vindoline, and catharanthine. Vinorelbine tartrate is a vinca alkaloid in which the catharanthine component is the target of structural modification 9, 10. This structural modification contributes to unique pharmacologic properties.The antitumor activity of vinorelbine tartrate is believed to be owed to the

Cabazitaxel is an anti cancer medicine and is used in the treatment of prostate cancer that has stopped responding to other anti cancer medicines or surgery.

Additional Information:

• Item Code: 30041010
• Production Capacity: KABANAT,CAZAT,CABAXAN,,JEVTANA,PROCABAZI,JEVTAXEL
• Delivery Time: 1
• Packaging Details: KABANAT,CAZAT,CABAXAN,,JEVTANA,PROCABAZI,JEVTAXEL

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